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Drug and xenobiotic biotransformation in the blood–brain barrier: a neglected issue
Drug biotransformation is a crucial mechanism for facilitating the elimination of chemicals from the organism and for decreasing their pharmacological activity. Published evidence suggests that brain drug metabolism may play a role in the development of adverse drug reactions and in the clinical res...
Autores principales: | Agúndez, José A. G., Jiménez-Jiménez, Félix J., Alonso-Navarro, Hortensia, García-Martín, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201098/ https://www.ncbi.nlm.nih.gov/pubmed/25368552 http://dx.doi.org/10.3389/fncel.2014.00335 |
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