Chemical Modulation of Mutant mGlu(1) Receptors Derived from Deleterious GRM1 Mutations Found in Schizophrenics

[Image: see text] Schizophrenia is a complex and highly heterogeneous psychiatric disorder whose precise etiology remains elusive. While genome-wide association studies (GWAS) have identified risk genes, they have failed to determine if rare coding single nucleotide polymorphisms (nsSNPs) contribute...

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Detalles Bibliográficos
Autores principales: Cho, Hyekyung P., Garcia-Barrantes, Pedro M., Brogan, John T., Hopkins, Corey R., Niswender, Colleen M., Rodriguez, Alice L., Venable, Daryl F., Morrison, Ryan D., Bubser, Michael, Daniels, J. Scott, Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201332/
https://www.ncbi.nlm.nih.gov/pubmed/25137254
http://dx.doi.org/10.1021/cb500560h

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