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Functional Evaluation of Key Interactions Evident in the Structure of the Eukaryotic Cys-Loop Receptor GluCl
[Image: see text] The publication of the first high-resolution crystal structure of a eukaryotic Cys-loop receptor, GluClα, has provided valuable structural information on this important class of ligand-gated ion channels (LGIC). However, limited functional data exist for the GluCl receptors. Before...
Autores principales: | Daeffler, Kristina N.-M., Lester, Henry A., Dougherty, Dennis A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201344/ https://www.ncbi.nlm.nih.gov/pubmed/25051140 http://dx.doi.org/10.1021/cb500323d |
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