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Nonmotor Symptoms in LRRK2 G2019S Associated Parkinson’s Disease

BACKGROUND: Idiopathic Parkinson’s disease (IPD) and LRRK2-associated PD (LRRK2-PD) might be expected to differ clinically since the neuropathological substrate of LRRK2-PD is heterogeneous. The range and severity of extra-nigral nonmotor features associated with LRRK2 mutations is also not well-def...

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Detalles Bibliográficos
Autores principales: Gaig, Carles, Vilas, Dolores, Infante, Jon, Sierra, María, García-Gorostiaga, Inés, Buongiorno, Mariateresa, Ezquerra, Mario, Martí, Maria José, Valldeoriola, Francesc, Aguilar, Miquel, Calopa, Matilde, Hernandez-Vara, Jorge, Tolosa, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201457/
https://www.ncbi.nlm.nih.gov/pubmed/25330404
http://dx.doi.org/10.1371/journal.pone.0108982