Mg(2+) Effect on Argonaute and RNA Duplex by Molecular Dynamics and Bioinformatics Implications

RNA interference (RNAi), mediated by small non-coding RNAs (e.g., miRNAs, siRNAs), influences diverse cellular functions. Highly complementary miRNA-target RNA (or siRNA-target RNA) duplexes are recognized by an Argonaute family protein (Ago2), and recent observations indicate that the concentration...

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Detalles Bibliográficos
Autores principales: Nam, Seungyoon, Ryu, Hyojung, Son, Won-joon, Kim, Yon Hui, Kim, Kyung Tae, Balch, Curt, Nephew, Kenneth P., Lee, Jinhyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201462/
https://www.ncbi.nlm.nih.gov/pubmed/25330448
http://dx.doi.org/10.1371/journal.pone.0109745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201462/
https://www.ncbi.nlm.nih.gov/pubmed/25330448
http://dx.doi.org/10.1371/journal.pone.0109745

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