THDP17 Decreases Ammonia Production through Glutaminase Inhibition. A New Drug for Hepatic Encephalopathy Therapy

Ammonia production is implicated in the pathogenesis of hepatic encephalopathy (HE), being intestinal glutaminase activity the main source for ammonia. Management of ammonia formation can be effective in HE treatment by lowering intestinal ammonia production. The use of glutaminase inhibitors repres...

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Detalles Bibliográficos
Autores principales: Díaz-Herrero, M. Mar, del Campo, José A., Carbonero-Aguilar, Pilar, Vega-Pérez, José M., Iglesias-Guerra, Fernando, Periñán, Ignacio, Miñano, Francisco J., Bautista, Juan, Romero-Gómez, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201470/
https://www.ncbi.nlm.nih.gov/pubmed/25329718
http://dx.doi.org/10.1371/journal.pone.0109787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201470/
https://www.ncbi.nlm.nih.gov/pubmed/25329718
http://dx.doi.org/10.1371/journal.pone.0109787

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