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Characterization of the Nuclear Import Mechanism of the CCAAT-Regulatory Subunit Php4

Php4 is a nucleo-cytoplasmic shuttling protein that accumulates in the nucleus during iron deficiency. When present in the nucleus, Php4 associates with the CCAAT-binding protein complex and represses genes encoding iron-using proteins. Here, we show that nuclear import of Php4 is independent of the...

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Detalles Bibliográficos
Autores principales: Khan, Md. Gulam Musawwir, Jacques, Jean-François, Beaudoin, Jude, Labbé, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201560/
https://www.ncbi.nlm.nih.gov/pubmed/25330182
http://dx.doi.org/10.1371/journal.pone.0110721