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Accurate Assignment of Significance to Neuropeptide Identifications Using Monte Carlo K-Permuted Decoy Databases
In support of accurate neuropeptide identification in mass spectrometry experiments, novel Monte Carlo permutation testing was used to compute significance values. Testing was based on k-permuted decoy databases, where k denotes the number of permutations. These databases were integrated with a rang...
Autores principales: | Akhtar, Malik N., Southey, Bruce R., Andrén, Per E., Sweedler, Jonathan V., Rodriguez-Zas, Sandra L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201571/ https://www.ncbi.nlm.nih.gov/pubmed/25329667 http://dx.doi.org/10.1371/journal.pone.0111112 |
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