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Global Epigenetic Regulation of MicroRNAs in Multiple Myeloma

Epigenetic changes frequently occur during tumorigenesis and DNA hypermethylation may account for the inactivation of tumor suppressor genes in cancer cells. Studies in Multiple Myeloma (MM) have shown variable DNA methylation patterns with focal hypermethylation changes in clinically aggressive sub...

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Detalles Bibliográficos
Autores principales: Zhang, Wenjing, Wang, Yaoyu E., Zhang, Yu, Leleu, Xavier, Reagan, Michaela, Zhang, Yong, Mishima, Yuji, Glavey, Siobhan, Manier, Salomon, Sacco, Antonio, Jiang, Bo, Roccaro, Aldo M., Ghobrial, Irene M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201574/
https://www.ncbi.nlm.nih.gov/pubmed/25330074
http://dx.doi.org/10.1371/journal.pone.0110973