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Measuring the Effect of Inter-Study Variability on Estimating Prediction Error

BACKGROUND: The biomarker discovery field is replete with molecular signatures that have not translated into the clinic despite ostensibly promising performance in predicting disease phenotypes. One widely cited reason is lack of classification consistency, largely due to failure to maintain perform...

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Detalles Bibliográficos
Autores principales: Ma, Shuyi, Sung, Jaeyun, Magis, Andrew T., Wang, Yuliang, Geman, Donald, Price, Nathan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201588/
https://www.ncbi.nlm.nih.gov/pubmed/25330348
http://dx.doi.org/10.1371/journal.pone.0110840