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Absence of Appl2 sensitizes endotoxin shock through activation of PI3K/Akt pathway

BACKGROUND: The adapter proteins Appl1 (adaptor protein containing pleckstrin homology domain, phosphotyrosine domain, and leucine zipper motif 1) and Appl2 are highly homologous and involved in several signaling pathways. While previous studies have shown that Appl1 plays a pivotal role in adiponec...

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Detalles Bibliográficos
Autores principales:	Mao, Liufeng, Lin, Wanhua, Nie, Tao, Hui, Xiaoyan, Gao, Xuefei, Li, Kuai, Ding, Mengxiao, Tang, Xiaofeng, Li, Peng, Wang, Yu, Xu, Aimin, Liu, Pentao, Wu, Donghai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201708/ https://www.ncbi.nlm.nih.gov/pubmed/25328665 http://dx.doi.org/10.1186/2045-3701-4-60

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