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Models of Impulsivity with a Focus on Waiting Impulsivity: Translational Potential for Neuropsychiatric Disorders

Waiting impulsivity, also known as premature or anticipatory responding, is well established in preclinical studies through the 5-Choice Serial Reaction Time (5-CSRT) task. Waiting impulsivity is important in disorders of addiction. Preclinical studies suggest a role both as a predictor, and as a co...

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Autor principal: Voon, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201744/
https://www.ncbi.nlm.nih.gov/pubmed/25346881
http://dx.doi.org/10.1007/s40429-014-0036-5
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author Voon, Valerie
author_facet Voon, Valerie
author_sort Voon, Valerie
collection PubMed
description Waiting impulsivity, also known as premature or anticipatory responding, is well established in preclinical studies through the 5-Choice Serial Reaction Time (5-CSRT) task. Waiting impulsivity is important in disorders of addiction. Preclinical studies suggest a role both as a predictor, and as a consequence, in disorders of addiction. Here we discuss the relationship between the preclinical 5-CSRT and translational fidelity in newly developed translational tasks. Preclinical and clinical literature relevant to premature responding and disorders of addiction are reviewed. Understanding which processes are critical to premature responding is important in understanding the nature of premature responding. Premature responding may also have overlaps with motivational processes, proactive response inhibition, tonic inhibitory processes, and delay discounting.
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spelling pubmed-42017442014-10-22 Models of Impulsivity with a Focus on Waiting Impulsivity: Translational Potential for Neuropsychiatric Disorders Voon, Valerie Curr Addict Rep Impulsivity (FG Moeller and D Ramesh, Section Editors) Waiting impulsivity, also known as premature or anticipatory responding, is well established in preclinical studies through the 5-Choice Serial Reaction Time (5-CSRT) task. Waiting impulsivity is important in disorders of addiction. Preclinical studies suggest a role both as a predictor, and as a consequence, in disorders of addiction. Here we discuss the relationship between the preclinical 5-CSRT and translational fidelity in newly developed translational tasks. Preclinical and clinical literature relevant to premature responding and disorders of addiction are reviewed. Understanding which processes are critical to premature responding is important in understanding the nature of premature responding. Premature responding may also have overlaps with motivational processes, proactive response inhibition, tonic inhibitory processes, and delay discounting. Springer International Publishing 2014-10-03 2014 /pmc/articles/PMC4201744/ /pubmed/25346881 http://dx.doi.org/10.1007/s40429-014-0036-5 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Impulsivity (FG Moeller and D Ramesh, Section Editors)
Voon, Valerie
Models of Impulsivity with a Focus on Waiting Impulsivity: Translational Potential for Neuropsychiatric Disorders
title Models of Impulsivity with a Focus on Waiting Impulsivity: Translational Potential for Neuropsychiatric Disorders
title_full Models of Impulsivity with a Focus on Waiting Impulsivity: Translational Potential for Neuropsychiatric Disorders
title_fullStr Models of Impulsivity with a Focus on Waiting Impulsivity: Translational Potential for Neuropsychiatric Disorders
title_full_unstemmed Models of Impulsivity with a Focus on Waiting Impulsivity: Translational Potential for Neuropsychiatric Disorders
title_short Models of Impulsivity with a Focus on Waiting Impulsivity: Translational Potential for Neuropsychiatric Disorders
title_sort models of impulsivity with a focus on waiting impulsivity: translational potential for neuropsychiatric disorders
topic Impulsivity (FG Moeller and D Ramesh, Section Editors)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201744/
https://www.ncbi.nlm.nih.gov/pubmed/25346881
http://dx.doi.org/10.1007/s40429-014-0036-5
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