The effect of polyhexamethylene guanidine hydrochloride (PHMG) derivatives introduced into polylactide (PLA) on the activity of bacterial enzymes

The present study was aimed at investigating bactericidal properties of polylactide (PLA) films containing three different polyhexamethylene guanidine hydrochloride (PHMG) derivatives and effect of the derivatives on extracellular hydrolytic enzymes and intracellular dehydrogenases. All PHMG derivat...

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Autores principales: Walczak, Maciej, Richert, Agnieszka, Burkowska-But, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Metabolic Engineering and Synthetic Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201754/
https://www.ncbi.nlm.nih.gov/pubmed/25189811
http://dx.doi.org/10.1007/s10295-014-1505-5
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author Walczak, Maciej
Richert, Agnieszka
Burkowska-But, Aleksandra
author_facet Walczak, Maciej
Richert, Agnieszka
Burkowska-But, Aleksandra
author_sort Walczak, Maciej
collection PubMed
description The present study was aimed at investigating bactericidal properties of polylactide (PLA) films containing three different polyhexamethylene guanidine hydrochloride (PHMG) derivatives and effect of the derivatives on extracellular hydrolytic enzymes and intracellular dehydrogenases. All PHMG derivatives had a slightly stronger bactericidal effect on Staphylococcus aureus than on E. coli but only PHMG granular polyethylene wax (at the concentration of at least 0.6 %) has a bactericidal effect. PHMG derivatives introduced into PLA affected the activity of microbial hydrolases to a small extent. This means that the introduction of PHMG derivatives into PLA will not reduce its enzymatic biodegradation significantly. On the other hand, PHMG derivatives introduced into PLA strongly affected dehydrogenases activity in S. aureus than in E. coli.
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spelling pubmed-42017542014-10-22 The effect of polyhexamethylene guanidine hydrochloride (PHMG) derivatives introduced into polylactide (PLA) on the activity of bacterial enzymes Walczak, Maciej Richert, Agnieszka Burkowska-But, Aleksandra J Ind Microbiol Biotechnol Metabolic Engineering and Synthetic Biology The present study was aimed at investigating bactericidal properties of polylactide (PLA) films containing three different polyhexamethylene guanidine hydrochloride (PHMG) derivatives and effect of the derivatives on extracellular hydrolytic enzymes and intracellular dehydrogenases. All PHMG derivatives had a slightly stronger bactericidal effect on Staphylococcus aureus than on E. coli but only PHMG granular polyethylene wax (at the concentration of at least 0.6 %) has a bactericidal effect. PHMG derivatives introduced into PLA affected the activity of microbial hydrolases to a small extent. This means that the introduction of PHMG derivatives into PLA will not reduce its enzymatic biodegradation significantly. On the other hand, PHMG derivatives introduced into PLA strongly affected dehydrogenases activity in S. aureus than in E. coli. Springer Berlin Heidelberg 2014-09-05 2014 /pmc/articles/PMC4201754/ /pubmed/25189811 http://dx.doi.org/10.1007/s10295-014-1505-5 Text en © The Author(s) 2014 https://creativecommons.org/licenses/by/4.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
spellingShingle Metabolic Engineering and Synthetic Biology
Walczak, Maciej
Richert, Agnieszka
Burkowska-But, Aleksandra
The effect of polyhexamethylene guanidine hydrochloride (PHMG) derivatives introduced into polylactide (PLA) on the activity of bacterial enzymes
title The effect of polyhexamethylene guanidine hydrochloride (PHMG) derivatives introduced into polylactide (PLA) on the activity of bacterial enzymes
title_full The effect of polyhexamethylene guanidine hydrochloride (PHMG) derivatives introduced into polylactide (PLA) on the activity of bacterial enzymes
title_fullStr The effect of polyhexamethylene guanidine hydrochloride (PHMG) derivatives introduced into polylactide (PLA) on the activity of bacterial enzymes
title_full_unstemmed The effect of polyhexamethylene guanidine hydrochloride (PHMG) derivatives introduced into polylactide (PLA) on the activity of bacterial enzymes
title_short The effect of polyhexamethylene guanidine hydrochloride (PHMG) derivatives introduced into polylactide (PLA) on the activity of bacterial enzymes
title_sort effect of polyhexamethylene guanidine hydrochloride (phmg) derivatives introduced into polylactide (pla) on the activity of bacterial enzymes
topic Metabolic Engineering and Synthetic Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201754/
https://www.ncbi.nlm.nih.gov/pubmed/25189811
http://dx.doi.org/10.1007/s10295-014-1505-5
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