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Prediction error demarcates the transition from retrieval, to reconsolidation, to new learning

Although disrupting reconsolidation is promising in targeting emotional memories, the conditions under which memory becomes labile are still unclear. The current study showed that post-retrieval changes in expectancy as an index for prediction error may serve as a read-out for the underlying process...

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Detalles Bibliográficos
Autores principales: Sevenster, Dieuwke, Beckers, Tom, Kindt, Merel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201815/
https://www.ncbi.nlm.nih.gov/pubmed/25320349
http://dx.doi.org/10.1101/lm.035493.114
Descripción
Sumario:Although disrupting reconsolidation is promising in targeting emotional memories, the conditions under which memory becomes labile are still unclear. The current study showed that post-retrieval changes in expectancy as an index for prediction error may serve as a read-out for the underlying processes engaged by memory reactivation. Minor environmental changes define whether retrieval induces memory reconsolidation or the initiation of a new memory trace even before fear extinction can be observed.