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Negative reinforcement impairs overnight memory consolidation
Post-learning sleep is beneficial for human memory. However, it may be that not all memories benefit equally from sleep. Here, we manipulated a spatial learning task using monetary reward and performance feedback, asking whether enhancing the salience of the task would augment overnight memory conso...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201816/ https://www.ncbi.nlm.nih.gov/pubmed/25320351 http://dx.doi.org/10.1101/lm.035196.114 |
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author | Stamm, Andrew W. Nguyen, Nam D. Seicol, Benjamin J. Fagan, Abigail Oh, Angela Drumm, Michael Lundt, Maureen Stickgold, Robert Wamsley, Erin J. |
author_facet | Stamm, Andrew W. Nguyen, Nam D. Seicol, Benjamin J. Fagan, Abigail Oh, Angela Drumm, Michael Lundt, Maureen Stickgold, Robert Wamsley, Erin J. |
author_sort | Stamm, Andrew W. |
collection | PubMed |
description | Post-learning sleep is beneficial for human memory. However, it may be that not all memories benefit equally from sleep. Here, we manipulated a spatial learning task using monetary reward and performance feedback, asking whether enhancing the salience of the task would augment overnight memory consolidation and alter its incorporation into dreaming. Contrary to our hypothesis, we found that the addition of reward impaired overnight consolidation of spatial memory. Our findings seemingly contradict prior reports that enhancing the reward value of learned information augments sleep-dependent memory processing. Given that the reward followed a negative reinforcement paradigm, consolidation may have been impaired via a stress-related mechanism. |
format | Online Article Text |
id | pubmed-4201816 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Cold Spring Harbor Laboratory Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-42018162015-11-01 Negative reinforcement impairs overnight memory consolidation Stamm, Andrew W. Nguyen, Nam D. Seicol, Benjamin J. Fagan, Abigail Oh, Angela Drumm, Michael Lundt, Maureen Stickgold, Robert Wamsley, Erin J. Learn Mem Brief Communication Post-learning sleep is beneficial for human memory. However, it may be that not all memories benefit equally from sleep. Here, we manipulated a spatial learning task using monetary reward and performance feedback, asking whether enhancing the salience of the task would augment overnight memory consolidation and alter its incorporation into dreaming. Contrary to our hypothesis, we found that the addition of reward impaired overnight consolidation of spatial memory. Our findings seemingly contradict prior reports that enhancing the reward value of learned information augments sleep-dependent memory processing. Given that the reward followed a negative reinforcement paradigm, consolidation may have been impaired via a stress-related mechanism. Cold Spring Harbor Laboratory Press 2014-11 /pmc/articles/PMC4201816/ /pubmed/25320351 http://dx.doi.org/10.1101/lm.035196.114 Text en © 2014 Stamm et al.; Published by Cold Spring Harbor Laboratory Press http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first 12 months after the full-issue publication date (see http://learnmem.cshlp.org/site/misc/terms.xhtml). After 12 months, it is available under a Creative Commons License (Attribution-NonCommercial 4.0 International), as described at http://creativecommons.org/licenses/by-nc/4.0/. |
spellingShingle | Brief Communication Stamm, Andrew W. Nguyen, Nam D. Seicol, Benjamin J. Fagan, Abigail Oh, Angela Drumm, Michael Lundt, Maureen Stickgold, Robert Wamsley, Erin J. Negative reinforcement impairs overnight memory consolidation |
title | Negative reinforcement impairs overnight memory consolidation |
title_full | Negative reinforcement impairs overnight memory consolidation |
title_fullStr | Negative reinforcement impairs overnight memory consolidation |
title_full_unstemmed | Negative reinforcement impairs overnight memory consolidation |
title_short | Negative reinforcement impairs overnight memory consolidation |
title_sort | negative reinforcement impairs overnight memory consolidation |
topic | Brief Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201816/ https://www.ncbi.nlm.nih.gov/pubmed/25320351 http://dx.doi.org/10.1101/lm.035196.114 |
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