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Detection of minimal residual disease in NPM1-mutated acute myeloid leukemia by next-generation sequencing
Detection of minimal residual disease predicts adverse outcome in patients with acute myeloid leukemia. Currently, minimal residual disease may be detected by RQ-PCR or flow cytometry, both of which have practical and diagnostic limitations. Here, we describe a next-generation sequencing assay for m...
Autores principales: | Salipante, Stephen J., Fromm, Jonathan R., Shendure, Jay, Wood, Brent L., Wu, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201902/ https://www.ncbi.nlm.nih.gov/pubmed/24743218 http://dx.doi.org/10.1038/modpathol.2014.57 |
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