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Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation
INTRODUCTION: Circulating histones have been identified as mediators of damage in animal models of sepsis and in patients with trauma-associated lung injury. Despite existing controversies on actual histone concentrations, clinical implications and mechanism of action in various disease conditions,...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201918/ https://www.ncbi.nlm.nih.gov/pubmed/25260379 http://dx.doi.org/10.1186/s13054-014-0543-8 |