N-Myc-induced up-regulation of TRPM6/TRPM7 channels promotes neuroblastoma cell proliferation

Intracellular levels of the divalent cations Ca(2+) and Mg(2+) are important regulators of cell cycle and proliferation. However, the precise mechanisms by which they are regulated in cancer remain incompletely understood. The channel kinases TRPM6 and TRPM7 are gatekeepers of human Ca(2+)/Mg(2+) me...

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Detalles Bibliográficos
Autores principales: Zhang, Zheng, Faouzi, Malika, Huang, Junhao, Geerts, Dirk, Yu, Haijie, Fleig, Andrea, Penner, Reinhold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202149/
https://www.ncbi.nlm.nih.gov/pubmed/25277194

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