Selective targeting of KRAS-Mutant cells by miR-126 through repression of multiple genes essential for the survival of KRAS-Mutant cells

MicroRNAs (miRNAs) regulate the expression of hundreds of genes. However, identifying the critical targets within a miRNA-regulated gene network is challenging. One approach is to identify miRNAs that exert a context-dependent effect, followed by expression profiling to determine how specific target...

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Detalles Bibliográficos
Autores principales: Hara, Toshifumi, Jones, Matthew F., Subramanian, Murugan, Li, Xiao Ling, Ou, Oliver, Zhu, Yuelin, Yang, Yuan, Wakefield, Lalage M., Hussain, S. Perwez, Gaedcke, Jochen, Ried, Thomas, Luo, Ji, Caplen, Natasha J., Lal, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202150/
https://www.ncbi.nlm.nih.gov/pubmed/25245095

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