MicroRNA-mediated down-regulation of NKG2D ligands contributes to glioma immune escape

Malignant gliomas are intrinsic brain tumors with a dismal prognosis. They are well-adapted to hypoxic conditions and poorly immunogenic. NKG2D is one of the major activating receptors of natural killer (NK) cells and binds to several ligands (NKG2DL). Here we evaluated the impact of miRNA on the ex...

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Detalles Bibliográficos
Autores principales: Codo, Paula, Weller, Michael, Meister, Gunter, Szabo, Emese, Steinle, Alexander, Wolter, Marietta, Reifenberger, Guido, Roth, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202151/
https://www.ncbi.nlm.nih.gov/pubmed/25277195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202151/
https://www.ncbi.nlm.nih.gov/pubmed/25277195

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