Metabolic effect of TAp63α: enhanced glycolysis and pentose phosphate pathway, resulting in increased antioxidant defense

TAp63α is a member of the p53 family, which plays a central role in epithelial cancers. Recently, a role has emerged for p53 family members in cancer metabolic modulation. In order to assess whether TAp63α plays a role in cancer metabolism, we exploited p53-null osteosarcoma Tet-On Saos-2 cells, in...

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Detalles Bibliográficos
Autores principales: D'Alessandro, Angelo, Amelio, Ivano, Berkers, Celia R., Antonov, Alexey, Vousden, Karen H., Melino, Gerry, Zolla, Lello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202156/
https://www.ncbi.nlm.nih.gov/pubmed/25229745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202156/
https://www.ncbi.nlm.nih.gov/pubmed/25229745

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