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A structural study for the optimisation of functional motifs encoded in protein sequences

BACKGROUND: A large number of PROSITE patterns select false positives and/or miss known true positives. It is possible that – at least in some cases – the weak specificity and/or sensitivity of a pattern is due to the fact that one, or maybe more, functional and/or structural key residues are not re...

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Detalles Bibliográficos
Autores principales: Via, Allegra, Helmer-Citterich, Manuela
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420233/
https://www.ncbi.nlm.nih.gov/pubmed/15119965
http://dx.doi.org/10.1186/1471-2105-5-50