Allelic dimorphism of the erythocyte binding antigen-175 (eba-175) gene of Plasmodium falciparum and severe malaria: Significant association of the C-segment with fatal outcome in Ghanaian children

BACKGROUND: The erythrocyte binding antigen-175 (EBA-175) on Plasmodium falciparum merozoites mediates sialic acid dependent binding to glycophorin A on host erythrocytes and, therefore, plays a crucial role in cell invasion. Dimorphic allele segments have been found in its encoding gene with a 342...

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Detalles Bibliográficos
Autores principales: Cramer, Jakob P, Mockenhaupt, Frank P, Möhl, Ingo, Dittrich, Sabine, Dietz, Ekkehardt, Otchwemah, Rowland N, Ehrhardt, Stephan, Bienzle, Ulrich, Jelinek, Tomas
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC420250/
https://www.ncbi.nlm.nih.gov/pubmed/15140262
http://dx.doi.org/10.1186/1475-2875-3-11

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