Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient

Congenital insensitivity to pain with anhidrosis is a rare disease of the nervous system which causes one to lose his/her feeling of pain. The disease is subtype four of hereditary sensory and autonomic neuropathy (HSAN IV) that results from NTRK1 gene defect. Direct sequencing was performed to scre...

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Autores principales: Saleh-gohari, Nasrollah, Mohammadi-Anaie, Marzye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Iranian Neuroscience Society 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202553/
https://www.ncbi.nlm.nih.gov/pubmed/25337332
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author Saleh-gohari, Nasrollah
Mohammadi-Anaie, Marzye
author_facet Saleh-gohari, Nasrollah
Mohammadi-Anaie, Marzye
author_sort Saleh-gohari, Nasrollah
collection PubMed
description Congenital insensitivity to pain with anhidrosis is a rare disease of the nervous system which causes one to lose his/her feeling of pain. The disease is subtype four of hereditary sensory and autonomic neuropathy (HSAN IV) that results from NTRK1 gene defect. Direct sequencing was performed to screen NTRK1 for mutations. The result revealed a homozygous deletion of adenine on intron 14 that may cause the disease.
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spelling pubmed-42025532014-10-21 Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient Saleh-gohari, Nasrollah Mohammadi-Anaie, Marzye Basic Clin Neurosci Case Report Congenital insensitivity to pain with anhidrosis is a rare disease of the nervous system which causes one to lose his/her feeling of pain. The disease is subtype four of hereditary sensory and autonomic neuropathy (HSAN IV) that results from NTRK1 gene defect. Direct sequencing was performed to screen NTRK1 for mutations. The result revealed a homozygous deletion of adenine on intron 14 that may cause the disease. Iranian Neuroscience Society 2013 /pmc/articles/PMC4202553/ /pubmed/25337332 Text en Copyright © 2013 Iranian Neuroscience Society http://creativecommons.org/licenses/by-nc/3.0/ This work is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.
spellingShingle Case Report
Saleh-gohari, Nasrollah
Mohammadi-Anaie, Marzye
Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient
title Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient
title_full Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient
title_fullStr Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient
title_full_unstemmed Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient
title_short Congenital Insensitivity to Pain with Anhidrosis in an Iranian Patient
title_sort congenital insensitivity to pain with anhidrosis in an iranian patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202553/
https://www.ncbi.nlm.nih.gov/pubmed/25337332
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