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Neph1 Is Reduced in Primary Focal Segmental Glomerulosclerosis, Minimal Change Nephrotic Syndrome, and Corresponding Experimental Animal Models of Adriamycin-Induced Nephropathy and Puromycin Aminonucleoside Nephrosis

BACKGROUND/AIMS: The transmembrane proteins Neph1 and nephrin form a complex in the slit diaphragm (SD) of podocytes. As recent studies indicate an involvement of this complex in the polymerization of the actin cytoskeleton and proteinuria, we wanted to study the subcellular localization of Neph1 in...

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Detalles Bibliográficos
Autores principales:	Hulkko, Jenny, Patrakka, Jaakko, Lal, Mark, Tryggvason, Karl, Hultenby, Kjell, Wernerson, Annika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2014
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202611/ https://www.ncbi.nlm.nih.gov/pubmed/25404935 http://dx.doi.org/10.1159/000365091

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