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A Vinyl Chloride-exposed Worker with an Adrenal Gland Angiosarcoma: A Case Report

Adrenal epithelioidangiosarcoma (AEA) is a rare neoplasm that accounts for less than 1% of sarcomas. Due to its rarity, it can easily be misdiagnosed, both by the clinician and the pathologist. Data on the patient’s occupational history was collected and analyzed. The bibliographic data was found on...

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Detalles Bibliográficos
Autores principales: CRISCUOLO, Mario, VALERIO, Jacqueline, GIANICOLO, Maria Elena, GIANICOLO, Emilio A.L, PORTALURI, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Occupational Safety and Health, Japan 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202765/
https://www.ncbi.nlm.nih.gov/pubmed/24292955
http://dx.doi.org/10.2486/indhealth.2013-0044
Descripción
Sumario:Adrenal epithelioidangiosarcoma (AEA) is a rare neoplasm that accounts for less than 1% of sarcomas. Due to its rarity, it can easily be misdiagnosed, both by the clinician and the pathologist. Data on the patient’s occupational history was collected and analyzed. The bibliographic data was found on the PUBMED bibliographic search site after entering the word “extrahepaticangiosarcoma”. We report a case of adrenal epithelioidangiosarcoma (AEA) in a 68 yr-old Caucasian male factory worker exposed to Vinyl Chloride (VC) for 15 yr. He underwent surgery, chemotherapy and radiotherapy. Hepatic angiosarcoma is a known consequence of VC exposure, but occupational causality of extra-hepatic angiosarcoma is controversial. Extra-hepatic angiosarcomas have been reported in VC workers, but never AEA. Cancerogenic effects of VC involve all endothelial areas of the body and extra-hepatic endothelial tumors may also be caused by this substance. This is the first published report of AEA diagnosed in a worker exposed to VC.