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Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE

OBJECTIVE: Studies evaluating T-cell recognition of myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis (MS) and its model, experimental autoimmune encephalomyelitis (EAE), have focused mostly on its 117 amino acid (aa) extracellular domain, especially peptide (p) 35-55. We characterized...

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Detalles Bibliográficos
Autores principales:	Shetty, Aparna, Gupta, Sheena G., Varrin-Doyer, Michel, Weber, Martin S., Prod'homme, Thomas, Molnarfi, Nicolas, Ji, Niannian, Nelson, Patricia A., Patarroyo, Juan C., Schulze-Topphoff, Ulf, Fogal, Stephen E., Forsthuber, Thomas, Sobel, Raymond A., Bernard, Claude C.A., Slavin, Anthony J., Zamvil, Scott S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202928/ https://www.ncbi.nlm.nih.gov/pubmed/25340074 http://dx.doi.org/10.1212/NXI.0000000000000022

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