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Epigenomic profiling of men exposed to early-life stress reveals DNA methylation differences in association with current mental state

Early-life stress (ELS) is known to be associated with an increased risk of neuropsychiatric and cardiometabolic disease in later life. One of the potential mechanisms underpinning this is through effects on the epigenome, particularly changes in DNA methylation. Using a well-phenotyped cohort of 83...

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Detalles Bibliográficos
Autores principales: Khulan, B, Manning, J R, Dunbar, D R, Seckl, J R, Raikkonen, K, Eriksson, J G, Drake, A J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203020/
https://www.ncbi.nlm.nih.gov/pubmed/25247593
http://dx.doi.org/10.1038/tp.2014.94