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High-resolution NMR studies of structure and dynamics of human ERp27 indicate extensive interdomain flexibility

ERp27 (endoplasmic reticulum protein 27.7 kDa) is a homologue of PDI (protein disulfide-isomerase) localized to the endoplasmic reticulum. ERp27 is predicted to consist of two thioredoxin-fold domains homologous with the non-catalytic b and b′ domains of PDI. The structure in solution of the N-termi...

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Detalles Bibliográficos
Autores principales: Amin, Nader T., Wallis, A. Katrine, Wells, Stephen A., Rowe, Michelle L., Williamson, Richard A., Howard, Mark J., Freedman, Robert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203274/
https://www.ncbi.nlm.nih.gov/pubmed/23234573
http://dx.doi.org/10.1042/BJ20121635

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