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Large-scale expansion of γδ T cells and peptide-specific cytotoxic T cells using zoledronate for adoptive immunotherapy

Specific cellular immunotherapy for cancer requires efficient generation and expansion of cytotoxic T lymphocytes (CTLs) that recognize tumor-associated antigens. However, it is difficult to isolate and expand functionally active T-cells ex vivo. In this study, we investigated the efficacy of a new...

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Detalles Bibliográficos
Autores principales: YOSHIKAWA, TOSHIAKI, TAKAHARA, MASASHI, TOMIYAMA, MAI, NIEDA, MIE, MAEKAWA, RYUJI, NAKATSURA, TETSUYA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203331/
https://www.ncbi.nlm.nih.gov/pubmed/25189159
http://dx.doi.org/10.3892/ijo.2014.2634