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Effective treatment of mitochondrial myopathy by nicotinamide riboside, a vitamin B3
Nutrient availability is the major regulator of life and reproduction, and a complex cellular signaling network has evolved to adapt organisms to fasting. These sensor pathways monitor cellular energy metabolism, especially mitochondrial ATP production and NAD(+)/NADH ratio, as major signals for nut...
Autores principales: | Khan, Nahid A, Auranen, Mari, Paetau, Ilse, Pirinen, Eija, Euro, Liliya, Forsström, Saara, Pasila, Lotta, Velagapudi, Vidya, Carroll, Christopher J, Auwerx, Johan, Suomalainen, Anu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203351/ https://www.ncbi.nlm.nih.gov/pubmed/24711540 http://dx.doi.org/10.1002/emmm.201403943 |
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