Cargando…
Thioredoxin-interacting protein regulates protein disulfide isomerases and endoplasmic reticulum stress
The endoplasmic reticulum (ER) is responsible for protein folding, modification, and trafficking. Accumulation of unfolded or misfolded proteins represents the condition of ER stress and triggers the unfolded protein response (UPR), a key mechanism linking supply of excess nutrients to insulin resis...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203352/ https://www.ncbi.nlm.nih.gov/pubmed/24843047 http://dx.doi.org/10.15252/emmm.201302561 |