Formation of Epichlorohydrin, a Known Rodent Carcinogen, Following Oral Administration of 1,3-Dichloro-2-propanol in Rats

[Image: see text] The observed toxicity and carcinogenicity of 1,3-dichloro-2-propanol (DCP) in rodents is thought to be due to the formation of reactive metabolites, epichlorohydrin (ECH) and dichloroacetone (DCA). However, there is no direct evidence for the formation of these metabolites from exp...

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Detalles Bibliográficos
Autores principales: Waidyanatha, Suramya, Gaudette, Norman F., Hong, Yan, Fennell, Timothy R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203385/
https://www.ncbi.nlm.nih.gov/pubmed/25254956
http://dx.doi.org/10.1021/tx500239q

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203385/
https://www.ncbi.nlm.nih.gov/pubmed/25254956
http://dx.doi.org/10.1021/tx500239q

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