A Chemoselective Route to β-Enamino Esters and Thioesters

[Image: see text] Conditions were developed for syntheses of β-enamino esters, thioesters, and amides. These reactions involve hydroxybenzotriazole derivatives in buffered media. Illustrative syntheses of some heterocyclic systems are given, including some related to protein–protein interface mimics...

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Detalles Bibliográficos
Autores principales: Xin, Dongyue, Burgess, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203388/
https://www.ncbi.nlm.nih.gov/pubmed/24679218
http://dx.doi.org/10.1021/ol5005643
Descripción
Sumario:[Image: see text] Conditions were developed for syntheses of β-enamino esters, thioesters, and amides. These reactions involve hydroxybenzotriazole derivatives in buffered media. Illustrative syntheses of some heterocyclic systems are given, including some related to protein–protein interface mimics.

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