Of microspheres and microbes: A double-hit strategy for cancer immunotherapy

Efficient immunotherapy relies on the rapid generation of elevated amounts of cancer-specific T lymphocytes. We have recently demonstrated that both rapid and potent tumor-targeting immune responses can be induced with a heterologous prime-boost regimen consisting of poly-lactic co-glycolic acid (PL...

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Detalles Bibliográficos
Autores principales: Brinkhoff, Benjamin, Wirth, Thomas C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203493/
https://www.ncbi.nlm.nih.gov/pubmed/25340000
http://dx.doi.org/10.4161/onci.27873
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author Brinkhoff, Benjamin
Wirth, Thomas C
author_facet Brinkhoff, Benjamin
Wirth, Thomas C
author_sort Brinkhoff, Benjamin
collection PubMed
description Efficient immunotherapy relies on the rapid generation of elevated amounts of cancer-specific T lymphocytes. We have recently demonstrated that both rapid and potent tumor-targeting immune responses can be induced with a heterologous prime-boost regimen consisting of poly-lactic co-glycolic acid (PLGA) microsphere-based immunization followed by Listeria monocytogenes infection.
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spelling pubmed-42034932015-02-14 Of microspheres and microbes: A double-hit strategy for cancer immunotherapy Brinkhoff, Benjamin Wirth, Thomas C Oncoimmunology Author's View Efficient immunotherapy relies on the rapid generation of elevated amounts of cancer-specific T lymphocytes. We have recently demonstrated that both rapid and potent tumor-targeting immune responses can be induced with a heterologous prime-boost regimen consisting of poly-lactic co-glycolic acid (PLGA) microsphere-based immunization followed by Listeria monocytogenes infection. Landes Bioscience 2014-02-14 /pmc/articles/PMC4203493/ /pubmed/25340000 http://dx.doi.org/10.4161/onci.27873 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Brinkhoff, Benjamin
Wirth, Thomas C
Of microspheres and microbes: A double-hit strategy for cancer immunotherapy
title Of microspheres and microbes: A double-hit strategy for cancer immunotherapy
title_full Of microspheres and microbes: A double-hit strategy for cancer immunotherapy
title_fullStr Of microspheres and microbes: A double-hit strategy for cancer immunotherapy
title_full_unstemmed Of microspheres and microbes: A double-hit strategy for cancer immunotherapy
title_short Of microspheres and microbes: A double-hit strategy for cancer immunotherapy
title_sort of microspheres and microbes: a double-hit strategy for cancer immunotherapy
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203493/
https://www.ncbi.nlm.nih.gov/pubmed/25340000
http://dx.doi.org/10.4161/onci.27873
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