Are natural killer cells superior CAR drivers?

T lymphocytes engineered to express a chimeric antigen receptor (CAR) are being celebrated as a major breakthrough of anticancer immunotherapy. Natural killer cells have not received similar attention as CAR effectors, although the use of these relatively short-lived cytotoxic cells is associated wi...

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Detalles Bibliográficos
Autor principal: Klingemann, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203506/
https://www.ncbi.nlm.nih.gov/pubmed/25340009
http://dx.doi.org/10.4161/onci.28147
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author Klingemann, Hans
author_facet Klingemann, Hans
author_sort Klingemann, Hans
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description T lymphocytes engineered to express a chimeric antigen receptor (CAR) are being celebrated as a major breakthrough of anticancer immunotherapy. Natural killer cells have not received similar attention as CAR effectors, although the use of these relatively short-lived cytotoxic cells is associated with several advantages.
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spelling pubmed-42035062015-04-15 Are natural killer cells superior CAR drivers? Klingemann, Hans Oncoimmunology Point of View T lymphocytes engineered to express a chimeric antigen receptor (CAR) are being celebrated as a major breakthrough of anticancer immunotherapy. Natural killer cells have not received similar attention as CAR effectors, although the use of these relatively short-lived cytotoxic cells is associated with several advantages. Landes Bioscience 2014-04-15 /pmc/articles/PMC4203506/ /pubmed/25340009 http://dx.doi.org/10.4161/onci.28147 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Point of View
Klingemann, Hans
Are natural killer cells superior CAR drivers?
title Are natural killer cells superior CAR drivers?
title_full Are natural killer cells superior CAR drivers?
title_fullStr Are natural killer cells superior CAR drivers?
title_full_unstemmed Are natural killer cells superior CAR drivers?
title_short Are natural killer cells superior CAR drivers?
title_sort are natural killer cells superior car drivers?
topic Point of View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203506/
https://www.ncbi.nlm.nih.gov/pubmed/25340009
http://dx.doi.org/10.4161/onci.28147
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