Suppression of MAPK/JNK-MTORC1 signaling leads to premature loss of organelles and nuclei by autophagy during terminal differentiation of lens fiber cells

Although autophagic pathways are essential to developmental processes, many questions still remain regarding the initiation signals that regulate autophagy in the context of differentiation. To address these questions we studied the ocular lens, as the programmed elimination of nuclei and organelles...

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Detalles Bibliográficos
Autores principales: Basu, Subhasree, Rajakaruna, Suren, Reyes, Beverly, Van Bockstaele, Elisabeth, Menko, A Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203547/
https://www.ncbi.nlm.nih.gov/pubmed/24813396
http://dx.doi.org/10.4161/auto.28768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203547/
https://www.ncbi.nlm.nih.gov/pubmed/24813396
http://dx.doi.org/10.4161/auto.28768

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