Reciprocal regulation of autophagy and dNTP pools in human cancer cells

Ribonucleotide reductase (RNR) plays a critical role in catalyzing the biosynthesis and maintaining the intracellular concentration of 4 deoxyribonucleoside triphosphates (dNTPs). Unbalanced or deficient dNTP pools cause serious genotoxic consequences. Autophagy is the process by which cytoplasmic c...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Zhang, Lisheng, Zhang, Keqiang, Zhou, Bingsen, Kuo, Mei-Ling, Hu, Shuya, Chen, Linling, Tang, Michelle, Chen, Yun-Ru, Yang, Lixin, Ann, David K, Yen, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Basic Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203552/
https://www.ncbi.nlm.nih.gov/pubmed/24905824
http://dx.doi.org/10.4161/auto.28954

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203552/
https://www.ncbi.nlm.nih.gov/pubmed/24905824
http://dx.doi.org/10.4161/auto.28954

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