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Reciprocal regulation of autophagy and dNTP pools in human cancer cells

Ribonucleotide reductase (RNR) plays a critical role in catalyzing the biosynthesis and maintaining the intracellular concentration of 4 deoxyribonucleoside triphosphates (dNTPs). Unbalanced or deficient dNTP pools cause serious genotoxic consequences. Autophagy is the process by which cytoplasmic c...

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Detalles Bibliográficos
Autores principales:	Chen, Wei, Zhang, Lisheng, Zhang, Keqiang, Zhou, Bingsen, Kuo, Mei-Ling, Hu, Shuya, Chen, Linling, Tang, Michelle, Chen, Yun-Ru, Yang, Lixin, Ann, David K, Yen, Yun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Basic Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203552/ https://www.ncbi.nlm.nih.gov/pubmed/24905824 http://dx.doi.org/10.4161/auto.28954

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