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KIAA1524/CIP2A promotes cancer growth by coordinating the activities of MTORC1 and MYC
KIAA1524/CIP2A/cancerous inhibitor of protein phosphatase 2A is a cancer-promoting protein that stabilizes the MYC proto-oncogene protein by inhibiting its dephosphorylation. Our recent report demonstrates that KIAA1524/CIP2A supports cancer cell growth also at the level of the mechanistic target of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203564/ https://www.ncbi.nlm.nih.gov/pubmed/24905455 http://dx.doi.org/10.4161/auto.29076 |