Prostate cancer: Important steps and considerations in the design of therapeutic vaccines

Vaccine-based immunotherapy can increase the overall survival of patients with advanced prostate cancer. However, the efficacy of vaccine-elicited anticancer immune responses is heavily influenced by the physical, nutritional, and psychological status of the patient. Given their importance, these pa...

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Detalles Bibliográficos
Autores principales: McArdle, Stephanie EB, Pockley, A Graham, Gibson, Glen R, Rees, Robert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203569/
https://www.ncbi.nlm.nih.gov/pubmed/25340006
http://dx.doi.org/10.4161/onci.28049
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author McArdle, Stephanie EB
Pockley, A Graham
Gibson, Glen R
Rees, Robert C
author_facet McArdle, Stephanie EB
Pockley, A Graham
Gibson, Glen R
Rees, Robert C
author_sort McArdle, Stephanie EB
collection PubMed
description Vaccine-based immunotherapy can increase the overall survival of patients with advanced prostate cancer. However, the efficacy of vaccine-elicited anticancer immune responses is heavily influenced by the physical, nutritional, and psychological status of the patient. Given their importance, these parameters should be carefully considered for the design of future clinical trials testing this immunotherapeutic paradigm in prostate cancer patients.
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spelling pubmed-42035692015-02-14 Prostate cancer: Important steps and considerations in the design of therapeutic vaccines McArdle, Stephanie EB Pockley, A Graham Gibson, Glen R Rees, Robert C Oncoimmunology Author's View Vaccine-based immunotherapy can increase the overall survival of patients with advanced prostate cancer. However, the efficacy of vaccine-elicited anticancer immune responses is heavily influenced by the physical, nutritional, and psychological status of the patient. Given their importance, these parameters should be carefully considered for the design of future clinical trials testing this immunotherapeutic paradigm in prostate cancer patients. Landes Bioscience 2014-02-14 /pmc/articles/PMC4203569/ /pubmed/25340006 http://dx.doi.org/10.4161/onci.28049 Text en Copyright © 2014 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
McArdle, Stephanie EB
Pockley, A Graham
Gibson, Glen R
Rees, Robert C
Prostate cancer: Important steps and considerations in the design of therapeutic vaccines
title Prostate cancer: Important steps and considerations in the design of therapeutic vaccines
title_full Prostate cancer: Important steps and considerations in the design of therapeutic vaccines
title_fullStr Prostate cancer: Important steps and considerations in the design of therapeutic vaccines
title_full_unstemmed Prostate cancer: Important steps and considerations in the design of therapeutic vaccines
title_short Prostate cancer: Important steps and considerations in the design of therapeutic vaccines
title_sort prostate cancer: important steps and considerations in the design of therapeutic vaccines
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203569/
https://www.ncbi.nlm.nih.gov/pubmed/25340006
http://dx.doi.org/10.4161/onci.28049
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