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Neonatal Fc receptors for IgG drive CD8(+) T cell-mediated anti-cancer immunosurveillance at tolerogenic mucosal sites
Mucosal boundaries, which are immunologically tolerogenic, and is further enhanced by undergo malignant transformation at high rates. We have identified the expression of neonatal Fc receptor for IgG (FcRn) by dendritic cells as a critical mediator of mucosal anti-cancer immunosurveillance. This dis...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203632/ https://www.ncbi.nlm.nih.gov/pubmed/25339998 http://dx.doi.org/10.4161/onci.27844 |