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Methotrexate-Related Response on Human Peripheral Blood Mononuclear Cells May Be Modulated by the Ala16Val-SOD2 Gene Polymorphism

Methotrexate (MTX) is a folic acid antagonist used in high doses as an anti-cancer treatment and in low doses for the treatment of some autoimmune diseases. MTX use has been linked to oxidative imbalance, which may cause multi-organ toxicities that can be attenuated by antioxidant supplementation. D...

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Detalles Bibliográficos
Autores principales:	Barbisan, Fernanda, Motta, Jéssica de Rosso, Trott, Alexis, Azzolin, Verônica, Dornelles, Eduardo Bortoluzzi, Marcon, Matheus, Algarve, Thaís Doeler, Duarte, Marta Maria Medeiros Frescura, Mostardeiro, Clarice Pinheiro, Unfer, Taís Cristina, Schott, Karen Lilian, da Cruz, Ivana Beatrice Mânica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203676/ https://www.ncbi.nlm.nih.gov/pubmed/25330300 http://dx.doi.org/10.1371/journal.pone.0107299

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