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Allosteric regulation of pentameric ligand-gated ion channels: An emerging mechanistic perspective

Pentameric ligand-gated ion channels (pLGICs) play a central role in intercellular communications in the nervous system by converting the binding of a chemical messenger—a neurotransmitter—into an ion flux through the postsynaptic membrane. They are oligomeric assemblies that provide prototypical ex...

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Detalles Bibliográficos
Autores principales:	Taly, Antoine, Hénin, Jérôme, Changeux, Jean-Pierre, Cecchini, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203737/ https://www.ncbi.nlm.nih.gov/pubmed/25478624 http://dx.doi.org/10.4161/chan.29444

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