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Impairment of Lysosomal Activity as a Therapeutic Modality Targeting Cancer Stem Cells of Embryonal Rhabdomyosarcoma Cell Line RD
Rhabdomyosarcoma is the most frequent soft tissue sarcoma in children and adolescents, with a high rate of relapse that dramatically affects the clinical outcome. Multiagent chemotherapy, in combination with surgery and/or radiation therapy, is the treatment of choice. However, the relapse rate is d...
Autores principales: | Salerno, Manuela, Avnet, Sofia, Bonuccelli, Gloria, Hosogi, Shigekuni, Granchi, Donatella, Baldini, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203792/ https://www.ncbi.nlm.nih.gov/pubmed/25329465 http://dx.doi.org/10.1371/journal.pone.0110340 |
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