Another “String to the Bow” of PJ34, a Potent Poly(ADP-Ribose)Polymerase Inhibitor: An Antiplatelet Effect through P2Y(12) Antagonism?

BACKGROUND: Neuro- and vasoprotective effects of poly(ADP-ribose)polymerase (PARP) inhibition have been largely documented in models of cerebral ischemia, particularly with the potent PARP inhibitor PJ34. Furthermore, after ischemic stroke, physicians are faced with incomplete tissue reperfusion and...

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Detalles Bibliográficos
Autores principales: Lechaftois, Marie, Dreano, Elise, Palmier, Bruno, Margaill, Isabelle, Marchand-Leroux, Catherine, Bachelot-Loza, Christilla, Lerouet, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203827/
https://www.ncbi.nlm.nih.gov/pubmed/25329809
http://dx.doi.org/10.1371/journal.pone.0110776

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