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Conformational Antibody Binding to a Native, Cell-Free Expressed GPCR in Block Copolymer Membranes
G-protein coupled receptors (GPCRs) play a key role in physiological processes and are attractive drug targets. Their biophysical characterization is, however, highly challenging because of their innate instability outside a stabilizing membrane and the difficulty of finding a suitable expression sy...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203850/ https://www.ncbi.nlm.nih.gov/pubmed/25329156 http://dx.doi.org/10.1371/journal.pone.0110847 |