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Identification of plant-derived natural products as potential inhibitors of the Mycobacterium tuberculosis proteasome

BACKGROUND: The Mycobacterium tuberculosis (Mtb) proteasome has been established as a viable target for the development of anti-tuberculosis agents. In this study, the inhibitory activities of 100 plant-derived natural products on the Mtb proteasome were analyzed to identify novel potential inhibito...

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Detalles Bibliográficos
Autores principales: Zheng, Yuejuan, Jiang, Xin, Gao, Feng, Song, Junxiang, Sun, Jinxia, Wang, Lixin, Sun, Xiaoxia, Lu, Zhenhui, Zhang, Huiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203866/
https://www.ncbi.nlm.nih.gov/pubmed/25315519
http://dx.doi.org/10.1186/1472-6882-14-400