Focal adhesion kinase is required for synovial fibroblast invasion, but not murine inflammatory arthritis

INTRODUCTION: Synovial fibroblasts invade cartilage and bone, leading to joint destruction in rheumatoid arthritis. However, the mechanisms that regulate synovial fibroblast invasion are not well understood. Focal adhesion kinase (FAK) has been implicated in cellular invasion in several cell types,...

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Detalles Bibliográficos
Autores principales: Shelef, Miriam A, Bennin, David A, Yasmin, Nihad, Warner, Thomas F, Ludwig, Thomas, Beggs, Hilary E, Huttenlocher, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203874/
https://www.ncbi.nlm.nih.gov/pubmed/25280866
http://dx.doi.org/10.1186/s13075-014-0464-6

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