Transcriptome-wide characterization of the eIF4A signature highlights plasticity in translation regulation

BACKGROUND: Protein synthesis is tightly regulated and alterations to translation are characteristic of many cancers. Translation regulation is largely exerted at initiation through the eukaryotic translation initiation factor 4 F (eIF4F). eIF4F is pivotal for oncogenic signaling as it integrates mi...

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Detalles Bibliográficos
Autores principales: Rubio, Claudia A, Weisburd, Benjamin, Holderfield, Matthew, Arias, Carolina, Fang, Eric, DeRisi, Joseph L, Fanidi, Abdallah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4203936/
https://www.ncbi.nlm.nih.gov/pubmed/25273840
http://dx.doi.org/10.1186/s13059-014-0476-1

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